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Pediatrics Flashcard
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- Fine, white scales without redness on the extensor surfaces of the extremities
- Improvement to rash in hot, humid climates and during the summer
- Hyperlinear palms and soles
- Caused by loss-of-function mutations in the gene encoding filaggrin
- Autosomal dominant
What disease has these characteristics?
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Answer
Ichthyosis vulgaris
Explanation
Ichthyosis vulgaris is the most common ichthyosis, occurring in 1/250 people. It is transmitted in an autosomal dominant fashion. Most commonly, the condition first manifests after 3 months of age. Treatment is irritant avoidance and use of emollients and keratolytic products.
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